Publications

Polstein, Lauren R., Mark Juhas, Gabi Hanna, Nenad Bursac, and Charles A. Gersbach. “An Engineered Optogenetic Switch for Spatiotemporal Control of Gene Expression, Cell Differentiation, and Tissue Morphogenesis.” ACS Synthetic Biology 6, no. 11 (November 2017): 2003–13. https://doi.org/10.1021/acssynbio.7b00147.

Cao, Jingli, Jinhu Wang, Christopher P. Jackman, Amanda H. Cox, Michael A. Trembley, Joseph J. Balowski, Ben D. Cox, et al. “Tension Creates an Endoreplication Wavefront that Leads Regeneration of Epicardial Tissue.” Dev Cell 42, no. 6 (September 25, 2017): 600-615.e4. https://doi.org/10.1016/j.devcel.2017.08.024.

Yanamandala, Mounica, Wuqiang Zhu, Daniel J. Garry, Timothy J. Kamp, Joshua M. Hare, Ho-Wook Jun, Young-Sup Yoon, et al. “Overcoming the Roadblocks to Cardiac Cell Therapy Using Tissue Engineering.” Journal of the American College of Cardiology 70, no. 6 (August 2017): 766–75. https://doi.org/10.1016/j.jacc.2017.06.012.

Bassat, Elad, Yara Eid Mutlak, Alex Genzelinakh, Ilya Y. Shadrin, Kfir Baruch Umansky, Oren Yifa, David Kain, et al. “The extracellular matrix protein agrin promotes heart regeneration in mice.” Nature 547, no. 7662 (July 2017): 179–84. https://doi.org/10.1038/nature22978.

Li, Yanzhen, Huda Asfour, and Nenad Bursac. “Age-dependent functional crosstalk between cardiac fibroblasts and cardiomyocytes in a 3D engineered cardiac tissue.” Acta Biomaterialia 55 (June 2017): 120–30. https://doi.org/10.1016/j.actbio.2017.04.027.

Liau, Brian, Christopher P. Jackman, Yanzhen Li, and Nenad Bursac. “Developmental stage-dependent effects of cardiac fibroblasts on function of stem cell-derived engineered cardiac tissues.” Scientific Reports 7 (February 2017): 42290. https://doi.org/10.1038/srep42290.

Gokhale, Tanmay A., Jong M. Kim, Robert D. Kirkton, Nenad Bursac, and Craig S. Henriquez. “Modeling an Excitable Biosynthetic Tissue with Inherent Variability for Paired Computational-Experimental Studies.” PLoS Computational Biology 13, no. 1 (January 2017): e1005342. https://doi.org/10.1371/journal.pcbi.1005342.

Pomeroy, Jordan E., Hung X. Nguyen, Brenton D. Hoffman, and Nenad Bursac. “Genetically Encoded Photoactuators and Photosensors for Characterization and Manipulation of Pluripotent Stem Cells.” Theranostics 7, no. 14 (2017): 3539–58. https://doi.org/10.7150/thno.20593.

Li, Yanzhen, Sophie Dal-Pra, Maria Mirotsou, Tilanthi M. Jayawardena, Conrad P. Hodgkinson, Nenad Bursac, and Victor J. Dzau. “Tissue-engineered 3-dimensional (3D) microenvironment enhances the direct reprogramming of fibroblasts into cardiomyocytes by microRNAs.” Sci Rep 6 (December 12, 2016): 38815. https://doi.org/10.1038/srep38815.

Jackman, Christopher P., Aaron L. Carlson, and Nenad Bursac. “Dynamic culture yields engineered myocardium with near-adult functional output.” Biomaterials 111 (December 2016): 66–79. https://doi.org/10.1016/j.biomaterials.2016.09.024.

Shadrin, I. Y., A. Khodabukus, and N. Bursac. “Striated muscle function, regeneration, and repair.” Cellular and Molecular Life Sciences : CMLS 73, no. 22 (November 2016): 4175–4202. https://doi.org/10.1007/s00018-016-2285-z.

Nguyen, Hung X., Robert D. Kirkton, and Nenad Bursac. “Engineering prokaryotic channels for control of mammalian tissue excitability.” Nature Communications 7 (October 2016): 13132. https://doi.org/10.1038/ncomms13132.

Ogle, Brenda M., Nenad Bursac, Ibrahim Domian, Ngan F. Huang, Philippe Menasché, Charles E. Murry, Beth Pruitt, et al. “Distilling complexity to advance cardiac tissue engineering.” Science Translational Medicine 8, no. 342 (June 2016): 342ps13. https://doi.org/10.1126/scitranslmed.aad2304.

Bursac, N. “Cardiac tissue engineering: Matching native architecture and function to develop safe and efficient therapy.” In Tissue Engineering and Artificial Organs, 877–900, 2016.

Juhas, Mark, Jean Ye, and Nenad Bursac. “Design, evaluation, and application of engineered skeletal muscle.” Methods (San Diego, Calif.) 99 (April 2016): 81–90. https://doi.org/10.1016/j.ymeth.2015.10.002.

Cheng, Cindy S., Lydia Ran, Nenad Bursac, William E. Kraus, and George A. Truskey. “Cell Density and Joint microRNA-133a and microRNA-696 Inhibition Enhance Differentiation and Contractile Function of Engineered Human Skeletal Muscle Tissues.” Tissue Eng Part A 22, no. 7–8 (April 2016): 573–83. https://doi.org/10.1089/ten.TEA.2015.0359.

Hung, Nguyen, and Nenad Bursac. “Engineering Prokaryotic Sodium Channels for Generation and Control of Mammalian Tissue Excitability.” In CIRCULATION, Vol. 134, 2016.

Albers, A., N. Bursac, and S. Rapp. “PGE - Product generation engineering - Case study of the dual mass flywheel.” In Proceedings of International Design Conference Design, DS 84:791–800, 2016.

Zhang, Hengtao, Albert Y. Sun, Jong J. Kim, Victoria Graham, Elizabeth A. Finch, Igor Nepliouev, Guiling Zhao, et al. “STIM1-Ca2+ signaling modulates automaticity of the mouse sinoatrial node.” In Proc Natl Acad Sci U S A, 112:E5618–27, 2015. https://doi.org/10.1073/pnas.1503847112.

Madden, L., C. Jackman, J. Wang, W. Kraus, G. Truskey, and N. Bursac. “Novel In Vitro Exercise Model of Engineered Human Skeletal Muscle.” In TISSUE ENGINEERING PART A, 21:S46–S46. MARY ANN LIEBERT, INC, 2015.

Juhas, M., J. Wang, J. Ye, I. Shadrin, and N. Bursac. “Engineering Regenerative Skeletal Muscle Tissues.” In TISSUE ENGINEERING PART A, 21:S310–S310. MARY ANN LIEBERT, INC, 2015.

Shadrin, Ilya Y., Woohyun Yoon, Liqing Li, Neal Shepherd, and Nenad Bursac. “Rapid fusion between mesenchymal stem cells and cardiomyocytes yields electrically active, non-contractile hybrid cells.” Scientific Reports 5 (July 2015): 12043. https://doi.org/10.1038/srep12043.

Madden, Lauran, Dwight Koeberl, and Nenad Bursac. “BIOENGINEERED HUMAN MUSCLE FOR PHYSIOLOGICAL STUDIES AND DISEASE MODELING.” In MOLECULAR GENETICS AND METABOLISM, 114:304–5. ACADEMIC PRESS INC ELSEVIER SCIENCE, 2015.

Jackman, Christopher P., Ilya Y. Shadrin, Aaron L. Carlson, and Nenad Bursac. “Human Cardiac Tissue Engineering: From Pluripotent Stem Cells to Heart Repair.” Current Opinion in Chemical Engineering 7 (February 2015): 57–64. https://doi.org/10.1016/j.coche.2014.11.004.

Madden, Lauran, Mark Juhas, William E. Kraus, George A. Truskey, and Nenad Bursac. “Bioengineered human myobundles mimic clinical responses of skeletal muscle to drugs.” Elife 4 (January 9, 2015): e04885. https://doi.org/10.7554/eLife.04885.