Publications

Pomeroy, Jordan E., and Nenad Bursac. “Selective Gq Activation in Cardiac Fibroblasts Decreases Isometric Force Generation in 3D Engineered Cardiac Tissues.” In CIRCULATION, Vol. 138, 2018.

Rao, Lingjun, Ying Qian, Alastair Khodabukus, Thomas Ribar, and Nenad Bursac. “Engineering human pluripotent stem cells into a functional skeletal muscle tissue.” Nature Communications 9, no. 1 (January 2018): 126. https://doi.org/10.1038/s41467-017-02636-4.

Rao, L., Y. Qian, A. Khodabukus, T. Ribar, and N. Bursac. “Contractile hPSC derived Skeletal Muscle Tissues for Human Disease Modeling.” In TISSUE ENGINEERING PART A, 23:S128–S128. MARY ANN LIEBERT, INC, 2017.

Juhas, M., N. O. Abutaleb, J. T. Wang, and N. Bursac. “Skeletal Muscle-Macrophage Platform for Modeling Tissue Regeneration.” In TISSUE ENGINEERING PART A, 23:S9–S9. MARY ANN LIEBERT, INC, 2017.

Wang, J., A. Khodabukus, M. Juhas, N. Abutaleb, and N. Bursac. “In Vitro Bioengineered Model for Studies of Human Muscle Regeneration.” In TISSUE ENGINEERING PART A, 23:S71–S71. MARY ANN LIEBERT, INC, 2017.

Khodabukus, A., L. Madden, C. Jackman, N. Prabhu, T. Koves, and N. Bursac. “Combined Drug and Electrical Stimulation Synergistically Increase Function of Engineered Human Skeletal Muscle.” In TISSUE ENGINEERING PART A, 23:S39–40. MARY ANN LIEBERT, INC, 2017.

Khodabukus, A., N. Prabhu, and N. Bursac. “Development of a Human Tissue-Engineered Model of Duchenne Muscular Dystrophy.” In TISSUE ENGINEERING PART A, 23:S115–S115. MARY ANN LIEBERT, INC, 2017.

Jackman, C. P., S. Heo, and N. Bursac. “Tissue-engineered Cardiobundles for In Vitro Development of Heart Regeneration Therapies.” In TISSUE ENGINEERING PART A, 23:S2–S2. MARY ANN LIEBERT, INC, 2017.

Li, Y., H. Asfour, L. Mao, H. A. Rockman, and N. Bursac. “3D Tissue-engineered Model of Pressure-overload Induced Cardiac Fibrosis.” In TISSUE ENGINEERING PART A, 23:S64–S64. MARY ANN LIEBERT, INC, 2017.

Shadrin, Ilya Y., Brian W. Allen, Ying Qian, Christopher P. Jackman, Aaron L. Carlson, Mark E. Juhas, and Nenad Bursac. “Cardiopatch platform enables maturation and scale-up of human pluripotent stem cell-derived engineered heart tissues.” Nat Commun 8, no. 1 (November 28, 2017): 1825. https://doi.org/10.1038/s41467-017-01946-x.

Polstein, Lauren R., Mark Juhas, Gabi Hanna, Nenad Bursac, and Charles A. Gersbach. “An Engineered Optogenetic Switch for Spatiotemporal Control of Gene Expression, Cell Differentiation, and Tissue Morphogenesis.” ACS Synthetic Biology 6, no. 11 (November 2017): 2003–13. https://doi.org/10.1021/acssynbio.7b00147.

Cao, Jingli, Jinhu Wang, Christopher P. Jackman, Amanda H. Cox, Michael A. Trembley, Joseph J. Balowski, Ben D. Cox, et al. “Tension Creates an Endoreplication Wavefront that Leads Regeneration of Epicardial Tissue.” Dev Cell 42, no. 6 (September 25, 2017): 600-615.e4. https://doi.org/10.1016/j.devcel.2017.08.024.

Yanamandala, Mounica, Wuqiang Zhu, Daniel J. Garry, Timothy J. Kamp, Joshua M. Hare, Ho-Wook Jun, Young-Sup Yoon, et al. “Overcoming the Roadblocks to Cardiac Cell Therapy Using Tissue Engineering.” Journal of the American College of Cardiology 70, no. 6 (August 2017): 766–75. https://doi.org/10.1016/j.jacc.2017.06.012.

Bassat, Elad, Yara Eid Mutlak, Alex Genzelinakh, Ilya Y. Shadrin, Kfir Baruch Umansky, Oren Yifa, David Kain, et al. “The extracellular matrix protein agrin promotes heart regeneration in mice.” Nature 547, no. 7662 (July 2017): 179–84. https://doi.org/10.1038/nature22978.

Li, Yanzhen, Huda Asfour, and Nenad Bursac. “Age-dependent functional crosstalk between cardiac fibroblasts and cardiomyocytes in a 3D engineered cardiac tissue.” Acta Biomaterialia 55 (June 2017): 120–30. https://doi.org/10.1016/j.actbio.2017.04.027.

Liau, Brian, Christopher P. Jackman, Yanzhen Li, and Nenad Bursac. “Developmental stage-dependent effects of cardiac fibroblasts on function of stem cell-derived engineered cardiac tissues.” Scientific Reports 7 (February 2017): 42290. https://doi.org/10.1038/srep42290.

Gokhale, Tanmay A., Jong M. Kim, Robert D. Kirkton, Nenad Bursac, and Craig S. Henriquez. “Modeling an Excitable Biosynthetic Tissue with Inherent Variability for Paired Computational-Experimental Studies.” PLoS Computational Biology 13, no. 1 (January 2017): e1005342. https://doi.org/10.1371/journal.pcbi.1005342.

Pomeroy, Jordan E., Hung X. Nguyen, Brenton D. Hoffman, and Nenad Bursac. “Genetically Encoded Photoactuators and Photosensors for Characterization and Manipulation of Pluripotent Stem Cells.” Theranostics 7, no. 14 (2017): 3539–58. https://doi.org/10.7150/thno.20593.

Li, Yanzhen, Sophie Dal-Pra, Maria Mirotsou, Tilanthi M. Jayawardena, Conrad P. Hodgkinson, Nenad Bursac, and Victor J. Dzau. “Tissue-engineered 3-dimensional (3D) microenvironment enhances the direct reprogramming of fibroblasts into cardiomyocytes by microRNAs.” Sci Rep 6 (December 12, 2016): 38815. https://doi.org/10.1038/srep38815.

Jackman, Christopher P., Aaron L. Carlson, and Nenad Bursac. “Dynamic culture yields engineered myocardium with near-adult functional output.” Biomaterials 111 (December 2016): 66–79. https://doi.org/10.1016/j.biomaterials.2016.09.024.

Shadrin, I. Y., A. Khodabukus, and N. Bursac. “Striated muscle function, regeneration, and repair.” Cellular and Molecular Life Sciences : CMLS 73, no. 22 (November 2016): 4175–4202. https://doi.org/10.1007/s00018-016-2285-z.

Nguyen, Hung X., Robert D. Kirkton, and Nenad Bursac. “Engineering prokaryotic channels for control of mammalian tissue excitability.” Nature Communications 7 (October 2016): 13132. https://doi.org/10.1038/ncomms13132.

Ogle, Brenda M., Nenad Bursac, Ibrahim Domian, Ngan F. Huang, Philippe Menasché, Charles E. Murry, Beth Pruitt, et al. “Distilling complexity to advance cardiac tissue engineering.” Science Translational Medicine 8, no. 342 (June 2016): 342ps13. https://doi.org/10.1126/scitranslmed.aad2304.

Bursac, N. “Cardiac tissue engineering: Matching native architecture and function to develop safe and efficient therapy.” In Tissue Engineering and Artificial Organs, 877–900, 2016.

Juhas, Mark, Jean Ye, and Nenad Bursac. “Design, evaluation, and application of engineered skeletal muscle.” Methods (San Diego, Calif.) 99 (April 2016): 81–90. https://doi.org/10.1016/j.ymeth.2015.10.002.