Welcome to the Bursac Lab

The main research focus of the Bursac Lab is the burgeoning field of regenerative medicine in which exogenous cells, molecules, or biomaterials are transplanted into the body to restore the function of damaged or diseased tissues and organs. Specifically, our group studies cardiac and skeletal muscle tissue engineering therapies, differentiation of pluripotent stem cells into striated muscle cells, and electrophysiology of excitable cells and tissues. These focus areas involve application of a variety of cell, tissue, and genetic engineering techniques to develop and study physiological model systems of striated muscles in vitro. Additionally, specialized electrophysiological and biomechanical studies are employed to evaluate the therapeutic potential of engineered cells and tissues in vivo.