Professor of Biomedical Engineering
Embryonic and adult stem cell therapies for heart and muscle disease; cardiac and skeletal muscle tissue engineering; cardiac electrophysiology and arrhythmias; genetic modifications of stem and somatic cells; micropatterning of proteins and hydrogels.
I will be performing rodent surgeries to support cardiac and skeletal muscle studies.
I work on developing more physiologically relevant tissue engineered skeletal muscle to study both healthy and diseased muscle physiology in human and rat cells.
I am working on human engineered skeletal and cardiac muscle for organ-on-chip studies.
I am interested in developing organ-on-chip platforms containing engineered cardiac and skeletal muscle microtissues to enable high throughput pharmacological and genome editing screening.
I am interested in developing functional neuromuscular junctions in vitro, the roles immune and glial cells play in the innervation of skeletal muscle, and regenerative strategies for the reinnervation of skeletal muscle following volumetric muscle loss in vivo.
I am interested in the fidelity of the electrical system and the role of fibroblasts in cardiac regeneration.
I am studying how the presence of immune cells affects the development and function of engineered skeletal muscle tissue.
I am working on cardiomyocyte proliferation in the context of regeneration.
I am interested in engineering skeletal muscle tissue and studying its regenerative capabilities in vitro.
I am interested in the functionality and regenerative capabilities of engineered skeletal muscle.
I work on human cardiac tissue engineering from pluripotent stem cells, and gene editing.
I am currently working on designing a stretch device to enhance the development and maturation of cardiac muscle tissue.
I am interested in the relationship between cardiac fibroblasts, cardiomyocytes, and the extracellular matrix as it relates to the biomechanics of cardiac disease and regeneration.
I am currently interested in studying the role of polyploidy in the context of proliferation and maturation of human iPSC-derived cardiomyocytes.
I am exploring methods to improve the regenerative capacity of engineered tissues derived from human skeletal muscle cells.
My research focuses on developing prokaryotic voltage-gated sodium channels (BacNav) based gene therapies for cardiac arrhythmias.
I am studying the proliferation of cardiomyocytes.
I am a sophomore at Duke pursuing a biology major on the pre-med track. In this lab, I will be helping study how the presence of immune cells effects the development and function of engineered skeletal muscle tissue.
I help with DNA mini and midi preps, the aliquoting of solutions, lab cleanup and maintenance, restocking items, and autoclaving standard laboratory materials.
I am currently working on the improvement of the structure and function of primary human and induced pluripotent stem cell engineered skeletal muscle tissues, which will be used for improved disease modeling of Duchenne muscular dystrophy and dysferlinopathy.
I am currently studying the development of engineered skeletal muscle tissue.
I am currently working on human cardiac tissue engineering from pluripotent stem cells.
I am currently studying methods to induce cardiomyocyte proliferation.
I am currently studying cardiomyocyte proliferation and maturation.
I am studying cardiomyocyte proliferation and gene therapies for cardiac arrhythmias.
I am studying the treatment of Pompe’s disease in engineered tissues derived from human skeletal muscle cells.