Professor of Biomedical Engineering
Embryonic and adult stem cell therapies for heart and muscle disease; cardiac and skeletal muscle tissue engineering; cardiac electrophysiology and arrhythmias; genetic modifications of stem and somatic cells; micropatterning of proteins and hydrogels.
I will be performing rodent surgeries to support cardiac and skeletal muscle studies.
I work on developing more physiologically relevant tissue engineered skeletal muscle to study both healthy and diseased muscle physiology in human and rat cells.
I am working on human engineered skeletal and cardiac muscle for organ-on-chip studies.
I am the lab manager for the Bursac Lab, and I also assist lab members with molecular biology and cell culture.
Associate in Research
I work with patient-derived cells in culture to better understand degenerative skeletal muscle diseases.
I am interested in developing organ-on-chip platforms containing engineered cardiac and skeletal muscle microtissues to enable high throughput pharmacological and genome editing screening.
I am a postdoctoral associate in biomedical engineering at Duke University. My research focuses on the application of cell therapy, cardiac tissue engineering, and genetic engineering to improve heart repair after myocardial infarction.
I study the mechanisms of ion channel trafficking in reponse to biomechanical cues.
I am interested in developing functional neuromuscular junctions in vitro, the roles immune and glial cells play in the innervation of skeletal muscle, and regenerative strategies for the reinnervation of skeletal muscle following volumetric muscle loss in vivo.
I am interested in the fidelity of the electrical system and the role of fibroblasts in cardiac regeneration.
I am studying how the presence of immune cells affects the development and function of engineered skeletal muscle tissue.
I am working on cardiomyocyte proliferation in the context of regeneration.
I work on human cardiac tissue engineering from pluripotent stem cells, and gene editing.
I study the effects of genetic modifications on skeletal muscle bundles in order to learn more about atherosclerosis.
I am currently interested in studying the role of polyploidy in the context of proliferation and maturation of human iPSC-derived cardiomyocytes.
I am exploring methods to improve the regenerative capacity of engineered tissues derived from human skeletal muscle cells.
I am studying the proliferation of cardiomyocytes.
I am currently working on the improvement of the structure and function of primary human and induced pluripotent stem cell engineered skeletal muscle tissues, which will be used for improved disease modeling of Duchenne muscular dystrophy and dysferlinopathy.
I am studying the treatment of Pompe’s disease in engineered tissues derived from human skeletal muscle cells.