Professor of Biomedical Engineering
Embryonic and adult stem cell therapies for heart and muscle disease; cardiac and skeletal muscle tissue engineering; cardiac electrophysiology and arrhythmias; genetic modifications of stem and somatic cells; micropatterning of proteins and hydrogels.
I work on developing more physiologically relevant tissue engineered skeletal muscle to study both healthy and diseased muscle physiology in human and rat cells.
I will provide Rodent surgery support for cardiac muscle and skeleton muscle tissue engineering studies.
I am interested in developing functional neuromuscular junctions in vitro, the roles immune and glial cells play in the innervation of skeletal muscle, and regenerative strategies for the reinnervation of skeletal muscle following volumetric muscle loss in vivo.
I am interested in the gene and cell therapy space. My current work focuses on optimizing BacNav based gene-therapies for increased efficacy.
I am studying how the presence of immune cells affects the development and function of engineered skeletal muscle tissue.
I am working on cardiomyocyte proliferation in the context of regeneration.
I am studying the role of macrophages in dysferlinopathy for their implementation in a tissue engineered skeletal muscle model.
I work on human cardiac tissue engineering from pluripotent stem cells, and gene editing.
I am interested in the relationship between neurons and cardiomyocytes in the context of cardiac innervation, regeneration, and disease.
I am interested in the relationship between cardiac fibroblasts, cardiomyocytes, and the extracellular matrix as it relates to the biomechanics of cardiac disease and regeneration.
I am currently interested in studying the role of polyploidy in the context of proliferation and maturation of human iPSC-derived cardiomyocytes.
My research focuses on developing prokaryotic voltage-gated sodium channels (BacNav) based gene therapies for cardiac arrhythmias.
I am interested in studying cardiomyocyte proliferation.
I'm interested in demonstrating a functional synaptic connection in a tissue-engineered model of the neuromuscular junction in order to study motor neuron innervation of muscle in healthy and diseased states.
I am a sophomore at Duke pursuing a biology major on the pre-med track. In this lab, I will be helping study how the presence of immune cells effects the development and function of engineered skeletal muscle tissue.
I am interested in developing prokaryotic sodium channel-based gene therapies for cardiac arrhythmias.
I am studying regenerative cardiomyocyte proliferation and working on developing an in vivo heart injury model.
I am currently studying methods to induce cardiomyocyte proliferation.
I am researching the mechanism behind cardiomyocyte proliferation for regenerative therapy application.
I am interested in the development and function of engineering skeletal muscle tissues.