Three-dimensional cultures of cardiomyocytes for electrophysiological studies of cardiac muscle

TitleThree-dimensional cultures of cardiomyocytes for electrophysiological studies of cardiac muscle
Publication TypeJournal Article
Year of Publication2000
AuthorsN Bursac, M Papadaki, J White, S Eisenberg, and L Freed
JournalAnnals of Biomedical Engineering
Volume28
IssueSUPPL. 1
Start PageS
PaginationS - 54
Date Published01/2000
Abstract

It was hypothesized that 3D cultures of cardiac myocytes consisting of multiple layers of interconnected cells would better mimic the structure and function of native tissue. Dissociated neonatal rat ventricular myocytes were seeded on 3D biodegradable polymer scaffolds and cultivated in a rotating tissue culture bioreactor for 7 days. In general, significant data was obtained.

Short TitleAnnals of Biomedical Engineering