Colonizing the heart from the epicardial side.

TitleColonizing the heart from the epicardial side.
Publication TypeJournal Article
Year of Publication2012
AuthorsBursac, N
JournalStem Cell Research and Therapy
Volume3
Issue2
Start Page15
Pagination15
Date Published04/2012
Abstract

The clinical use of stem cells, such as bone marrow-derived and, more recently, resident cardiac stem cells, offers great promise for treatment of myocardial infarction and heart failure. The epicardium-derived cells have also attracted attention for their angiogenic paracrine actions and ability to differentiate into cardiomyocytes and vascular cells when activated during cardiac injury. In a recent study, Chong and colleagues have described a distinct population of epicardium-derived mesenchymal stem cells that reside in a perivascular niche of the heart and have a broad multilineage potential. Exploring the therapeutic capacity of these cells will be an exciting future endeavor.

DOI10.1186/scrt106
Short TitleStem Cell Research and Therapy