Colonizing the heart from the epicardial side.

TitleColonizing the heart from the epicardial side.
Publication TypeJournal Article
Year of Publication2012
AuthorsN Bursac
JournalStem Cell Research and Therapy
Volume3
Issue2
Start Page15
Pagination15
Date Published04/2012
Abstract

The clinical use of stem cells, such as bone marrow-derived and, more recently, resident cardiac stem cells, offers great promise for treatment of myocardial infarction and heart failure. The epicardium-derived cells have also attracted attention for their angiogenic paracrine actions and ability to differentiate into cardiomyocytes and vascular cells when activated during cardiac injury. In a recent study, Chong and colleagues have described a distinct population of epicardium-derived mesenchymal stem cells that reside in a perivascular niche of the heart and have a broad multilineage potential. Exploring the therapeutic capacity of these cells will be an exciting future endeavor.

DOI10.1186/scrt106
Short TitleStem Cell Research and Therapy